One suppository contains: Samprosta substance, based on the 20% content of water-soluble peptides – 100 mg lomefloxacin hydrochloride 400 mg and excipient – suppository base: a hard fat (Witepsol) – a sufficient amount to obtain a suppository weighing 2.25 g
Description laisa andriol from white or nearly white to light cream with a grayish shade, Valium forms.
Means of treatment of chronic prostatitis
Combined preparation Vitaprost® Plus has antimicrobial and anti-inflammatory properties.
Lomefloksatsin – antibacterial broad spectrum of action of the fluoroquinolones. It affects the bacterial enzyme DNA gyrase, which provides supercoiling forms a complex with its tetramer (A2B2 subunit of gyrase) and disrupts DNA replication and transcription, leading to bacterial cell death. Highly active against gram-negative aerobic organisms: Neisseria gonorrhoeae, Neisseria meningitides, Escherichia coli, Citrobacter diversus, Klebsiella pneumoniae, Enterobacter cloacae, Proteus vulgaris, Salmonella spp, Shigella spp, Moraxella morganii, Haemophilus influenzae e parainfluenzae, Legionella pneumophila, Pseudomonas aeruginosa.. . Moderately susceptible to the drug Staphylococcus aureus, Staphylococcus Epidermidis, Serratia liquifaciens, Serratia marcescens, Pseudomonas aeruginosa, Mycobacterium tuberculosis, Chlamydia trachomatis, Hafnia alvei, Citrobacter freundii, Aeromonas hydrophila, Proteus mirabilis, Proteus stuartii, Providencia rettgeri, Providencia alcalifaciens, Klebsiella oxytoca, Klebsiella ozaenae, Enterobacter aerogenes, Enterobacter agglomerans. Drug resistance Streptococcus spp., Pseudomonas cepacia, Ureaplasma urealyticum, Treponema pallidum, Mycoplasma hominis and anaerobic bacteria. In most microbial effect at low concentrations (concentration required to inhibit 90% growth of strains, typically less than 1 ug / ml). Resistance is rare.
Prostate Organotropona extract has effect on the prostate. Reduces the degree of edema, leukocyte infiltration of the prostate, normalizes secretory function of epithelial cells, increases the number of lecithin granules secret acini, stimulates the muscle tone of the bladder. It reduces blood clots, has antiplatelet activity, prevents the development of thrombosis of venules in the prostate gland. It normalizes prostate and semen parameters. It reduces pain and discomfort, improves the copulatory function.
Acute and chronic bacterial prostatitis caused by susceptible organisms, including those accompanied by inflammatory diseases of the urinary tract.
States before and after surgery on the prostate gland.
Hypersensitivity to the drug.
Age 18 years (during the formation and growth of the skeleton).
Cerebral atherosclerosis, epilepsy and other central nervous system diseases with epileptic syndrome.
Dosing and Administration
Rectal, 1 suppository 1 time a day after the enema or self-emptying of the bowel. Before applying the suppository should be removed from the blisters. After administration Vitaprost® Plus desirable for 30-40 minutes to be in bed. The course of treatment is continued until the disappearance of the pathogen in prostatic secretions and is 10 to 30 days (the duration of treatment is determined by the physician individually for each patient).
Side effects of the drug Vitaprost® Plus, due to the presence in its composition of antibiotic lomefloxacin.
Allergic reactions: itching, rash, photosensitivity, malignant laisa andriol exudative erythema (Stevens-Johnson syndrome).
From the nervous system: asthenia, dizziness, nervousness, anxiety.
From the digestive system: pseudomembranous enterocolitis, dysbiosis, increased activity of “liver” transaminases.
From the side of hematopoiesis and hemostasis system: bleeding from the gastrointestinal tract, anemia, increased fibrinolysis, lymphadenopathy.
Since the cardiovascular system: blood pressure reduction, dysrhythmia, cardiomyopathy.
Substance Samprost (prostate extract) rarely causes allergic reactions.
Increases activity oral anticoagulants and increases the toxicity of nonsteroidal anti-inflammatory drugs.
Drugs that block tubular secretion, slow down the excretion of the drug.
No cross-resistance with penicillins, cephalosporins, aminoglycosides, co-trimoxazole, metronidazole.
In cirrhosis of the liver does not require correction dosing regimen (assuming normal renal function).
During treatment should avoid prolonged exposure to sunlight and the use of artificial ultraviolet light. At the first sign of photosensitivity (increased sensitivity of the skin, burns, redness, swelling, blisters, rash, itching, dermatitis) hypersensitivity manifestations of neurotoxicity (agitation, convulsions, tremors, photophobia, confusion, toxic psychosis, hallucinations) therapy should be discontinued.
During the period of treatment must be careful when driving and occupation of other potentially hazardous activities that require high concentration and psychomotor speed reactions.